Business Disruption, AI-Assisted Attacks, Insider Threats and Accelerated Intrusions on Multiple Fronts Define the New Cyberthreat Landscape

Palo Alto Networks Unit 42 today released its 2025 Global Incident Response Report, revealing that 86% of major cyber incidents in 2024 resulted in operational downtime, reputational damage or financial loss. The report (based on 500 major cyber incidents that Unit 42 responded to across 38 countries and every major industry) highlights a new trend: financially motivated attackers have shifted their focus to deliberate operational disruption, prioritizing sabotage – destroying systems, locking customers out and causing prolonged downtime – to maximize impact and pressure organizations into paying extortion demands.

The speed, sophistication and scale of attacks have reached unprecedented levels with AI-assisted threats and multipronged intrusions, underscoring that organizations faced an increasingly volatile threat landscape in 2024.

Key Findings — Cyberthreats Move Faster and Hit Harder

As attackers rewrite the rules of engagement, defenders scramble to keep up. The attacker’s new playbook is multipronged, cloud-focused and AI-driven. The 2025 Global Incident Response Report highlights several trends:

Why Cyberattacks Succeed — Attackers Exploit Complexity, Visibility Gaps and Excessive Trust

The report underscores three primary enablers that are allowing adversaries to succeed:

Attackers have rewritten their playbooks leveraging AI, automation and multipronged attack strategies to bypass traditional defenses. The time between initial compromise and full-scale impact is shrinking, making rapid detection, response and remediation critical.

The key to staying ahead in 2025 is to proactively secure networks, applications and cloud, as well as empower security operations with AI-driven detection and response for full visibility and faster threat mitigation.

Defenders need to adapt as the attacker playbook evolves. Stay informed, view the 2025 Unit 42 Global Incident Response Report.

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